Ching-Liang Hsieh Selected Research

rhyncophylline

5/2014	Uncaria rhynchophylla and rhynchophylline improved kainic acid-induced epileptic seizures via IL-1β and brain-derived neurotrophic factor.
1/2013	Antiepileptic Effect of Uncaria rhynchophylla and Rhynchophylline Involved in the Initiation of c-Jun N-Terminal Kinase Phosphorylation of MAPK Signal Pathways in Acute Seizures of Kainic Acid-Treated Rats.
5/2009	Rhynchophylline from Uncaria rhynchophylla functionally turns delayed rectifiers into A-Type K+ channels.
1/2009	Uncaria rhynchophylla and Rhynchophylline inhibit c-Jun N-terminal kinase phosphorylation and nuclear factor-kappaB activity in kainic acid-treated rats.

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Ching-Liang Hsieh Research Topics

Disease

24	Pain (Aches) 01/2021 - 10/2002
18	Cerebral Infarction 01/2017 - 01/2003
17	Inflammation (Inflammations) 01/2021 - 05/2008
12	Brain Ischemia (Cerebral Ischemia) 11/2018 - 01/2006
10	Ischemia 07/2021 - 01/2003
10	Hyperalgesia 07/2020 - 11/2011
10	Seizures (Absence Seizure) 01/2018 - 09/2004
9	Body Weight (Weight, Body) 06/2022 - 01/2008
9	Reperfusion Injury 01/2021 - 05/2008
9	Epilepsy (Aura) 01/2021 - 01/2007
9	Stroke (Strokes) 04/2018 - 01/2006
7	Neoplasms (Cancer) 02/2022 - 01/2014
7	Fibromyalgia (Fibrositis) 07/2020 - 01/2015
5	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2017 - 05/2008
4	Obesity 06/2022 - 01/2009
4	Infarction (Infarctions) 01/2021 - 01/2014
4	Dementia (Dementias) 06/2020 - 01/2005
4	Parkinson Disease (Parkinson's Disease) 06/2020 - 04/2017
4	Neuralgia (Stump Neuralgia) 01/2020 - 01/2014
3	Hypertension (High Blood Pressure) 06/2022 - 01/2004
3	Ischemic Stroke 01/2021 - 01/2012
3	Nervous System Diseases (Neurological Disorders) 06/2020 - 05/2009
3	Migraine Disorders (Migraine) 10/2019 - 11/2013
3	Hypesthesia (Numbness) 01/2018 - 01/2009
3	Infections 01/2018 - 09/2004
3	Postoperative Pain 12/2015 - 10/2002
2	Schizophrenia (Dementia Praecox) 06/2022 - 01/2012
2	Osteoarthritis 01/2021 - 10/2015
2	Alzheimer Disease (Alzheimer's Disease) 06/2020 - 01/2020
2	Arthritis (Polyarthritis) 01/2020 - 01/2015
2	Atopic Dermatitis (Atopic Eczema) 01/2020 - 03/2016
2	Diarrhea 06/2019 - 03/2019
2	Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy) 05/2019 - 09/2010
2	Nausea 03/2019 - 10/2002
2	Wounds and Injuries (Trauma) 01/2019 - 04/2017
2	Suppuration 04/2017 - 03/2016
2	Hypoxia (Hypoxemia) 01/2017 - 01/2010
2	Atrophy 03/2016 - 01/2007
2	Neuroblastoma 01/2016 - 05/2009
2	Gliosis 01/2016 - 07/2015
2	Hypoglycemia (Reactive Hypoglycemia) 01/2015 - 01/2005

Drug/Important Bio-Agent (IBA)

10	Kainic Acid (Kainate)IBA 01/2018 - 01/2007
9	Proteins (Proteins, Gene)FDA Link 07/2021 - 01/2010
8	salicylhydroxamic acid (SHAM)IBA 01/2021 - 10/2002
8	Neuroprotective AgentsIBA 01/2017 - 05/2008
7	Therapeutic UsesIBA 02/2022 - 01/2010
7	Freund's AdjuvantIBA 12/2019 - 11/2011
5	CytokinesIBA 01/2021 - 12/2016
5	Analgesics (Analgesic Drugs)IBA 06/2020 - 03/2014
5	p38 Mitogen-Activated Protein KinasesIBA 06/2020 - 01/2014
4	AcidsIBA 01/2020 - 01/2015
4	Opioid Analgesics (Opioids)IBA 11/2017 - 10/2002
4	Blood Glucose (Blood Sugar)IBA 02/2017 - 06/2006
4	paeonolIBA 01/2016 - 06/2006
4	rhyncophyllineIBA 05/2014 - 01/2009
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 01/2010
3	Anticonvulsants (Antiepileptic Drugs)IBA 01/2021 - 01/2009
3	AntioxidantsIBA 03/2020 - 08/2011
3	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2020 - 07/2011
3	ChemokinesIBA 01/2020 - 01/2017
3	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2019 - 01/2008
3	Adenosine (Adenocard)FDA LinkGeneric 11/2017 - 01/2017
3	Mitogen-Activated Protein KinasesIBA 01/2017 - 07/2015
3	SteroidsIBA 03/2016 - 05/2009
3	ferulic acid (sodium ferulate)IBA 01/2016 - 01/2008
3	JNK Mitogen-Activated Protein KinasesIBA 01/2013 - 01/2007
3	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2010 - 01/2008
3	Interleukin-1beta (Interleukin 1 beta)IBA 01/2010 - 01/2005
3	Superoxides (Superoxide)IBA 01/2009 - 06/2006
2	N-Methylaspartate (NMDA)IBA 01/2021 - 09/2010
2	Sodium Channels (Sodium Channel)IBA 01/2021 - 01/2013
2	Acid Sensing Ion ChannelsIBA 01/2020 - 11/2011
2	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2020 - 01/2015
2	Bee Venoms (Bee Venom)IBA 01/2020 - 01/2015
2	Transient Receptor Potential ChannelsIBA 01/2020 - 09/2019
2	Toll-Like Receptor 2IBA 12/2019 - 01/2016
2	Nitroglycerin (Dynamite)FDA LinkGeneric 10/2019 - 01/2019
2	polyglutamineIBA 02/2019 - 01/2016
2	peoniflorinIBA 11/2018 - 01/2010
2	Toll-Like Receptor 4IBA 01/2018 - 01/2016
2	N(6)-cyclopentyladenosineIBA 11/2017 - 01/2017
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 04/2017 - 03/2017
2	SB 203580IBA 01/2017 - 01/2016
2	Caspase 3 (Caspase-3)IBA 01/2017 - 01/2016
2	10,10'-dimethyl-9,9'-biacridinium (Lucigenin)IBA 12/2016 - 01/2003
2	Free RadicalsIBA 12/2016 - 01/2007

Therapy/Procedure

36	Electroacupuncture 01/2021 - 10/2002
21	Acupuncture Points (Acupuncture Point) 01/2021 - 10/2002
15	Chinese Traditional Medicine (Traditional Chinese Medicine) 06/2022 - 01/2003
15	Therapeutics 02/2022 - 09/2004
9	Oral Administration 09/2022 - 01/2012
6	Injections 07/2020 - 01/2015
4	Analgesia 12/2019 - 01/2017
3	Ear Acupuncture 01/2020 - 01/2009
3	Acupuncture Therapy 01/2020 - 01/2004
3	Complementary Therapies (Alternative Medicine) 01/2014 - 10/2010
2	Acupressure (Shiatsu) 05/2020 - 01/2012
2	Intraperitoneal Injections 10/2019 - 01/2003
2	Sutures (Suture) 05/2019 - 01/2014
2	Vagus Nerve Stimulation 12/2018 - 01/2014